Induction of anti-idiotypic humoral and cellular immune responses by a murine monoclonal antibody recognizing the ovarian carcinoma antigen CA125 encapsulated in biodegradable microspheres

Induction of cellular immune responses b

Induction of cellular immune responses by a murine monoclonal anti-idiotypic antibody recognizing the 791tgp72 antigen expressed on colorectal, gastric and ovarian human tumours

✍ Lindy G. Durrant; Mark Doran; Eric B. Austin; R. Adrian Robins 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 525 KB

There is accumulating evidence that cellular rather than antibody responses are more effective for tumour rejection. It is therefore important to screen anti-idiotypic (anti-id) antibodies for their ability to stimulate anti-tumour T-cell responses. The human anti-id monoclonal antibody (MAb) I05AD7