Because the biological spectrum of human papillomavirus (HPV) genotypes present in cervical cancer lesions varies according to the geographical region studied, and because little genotype information is available for Central and Eastern European countries, we studied the endemic HPV-genotype spectru
Induction of an antibody response in mice against human papillomavirus (HPV) type 16 after immunization with HPV recombinantSalmonellastrains
β Scribed by M. R. L. Krul; Edwin J. Tijhaar; John A. F. W. Kleijne; Anton M. Van Loon; Mirjam G. Nievers; Hans Schipper; Liesbeth Geerse; M. Van der Kolk; Peter A. Steerenberg; Frits R. Mooi; Willem Den Otter
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 137 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0340-7004
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## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh
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## Abstract Specific types of human papillomavirus (HPV) are known to play a causal role in the development of cervical cancer, with human papillomavirus type 16 (HPVβ16) identified as the predominant type. Despite this, little is known about cervical immune responses to this pathogen. The aim of t