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Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells

โœ Scribed by Yoshifumi Sachi; Kiichi Hirota; Hiroshi Masutani; Ken-ichi Toda; Takashi Okamoto; Masahiro Takigawa; Junji Yodoi


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
724 KB
Volume
44
Category
Article
ISSN
0165-2478

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Oxygen is essential for aerobic life, although reactive oxygen intermediates can be highly toxic to cells. Superoxide radicals and hydrogen peroxide become particularly harmful __in vivo__ due to their reactivity with transition metals like iron, producing hydroxyl radicals, which are involved in DN