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Induction of accommodation in the hamster-to-rat model requires inhibition of the membrane attack complex of complement

✍ Scribed by B.D Suhr; M Guzman-Paz; E.P Apasova; A.J Matas; A.P Dalmasso

Book ID: 117229149
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 42 KB
Volume: 32
Category: Article
ISSN: 0041-1345
DOI: 10.1016/s0041-1345(00)01072-1

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## Abstract The membranolytic C5b‐9 complement membrane attack complex (MAC) is assembled after activation of either the classic or the alternative complement pathway. The quaternary configuration of the MAC macromolecule presents neoantigenic determinants not present on precursor molecules. Conseq