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Induction of a CD8+ T Cell Response to Tumor Antigens Is Associated with Improved Survival in Patients Transplanted for Acute Myeloid Leukemia

✍ Scribed by Nagra, Sandeep; Goodyear, Oliver Charles; Khan, Josephine; Jilani, Nadira Yasmin; Ferguson, Paul; Russell, Nigel; Dennis, Mike; Vyas, Paresh; Siddique, Shamyla; Craddock, Charles


Book ID
122255675
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
52 KB
Volume
20
Category
Article
ISSN
1083-8791

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## Abstract Regulatory T cells (Treg) mediate amelioration of disease and immune homeostasis by inhibiting immune activation and maintaining peripheral immune tolerance. The suppressive mechanisms and clinical significance of Treg have not been completely elucidated in patients with acute myeloid l