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Induction and inhibition of amphibian (Rana pipiens) oocyte maturation by protease inhibitor (TPCK)

โœ Scribed by Ishikawa, Katsutoshi ;Schuetz, Allen W. ;Francisco, S. K. San

Book ID
111663447
Publisher
Wiley (John Wiley & Sons)
Year
1989
Weight
902 KB
Volume
22
Category
Article
ISSN
0148-7280

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In view of recent reports on the production of inhibin-and activin-like proteins in lower vertebrates and their important role during development, we have examined the effects of the gonadopeptide inhibin in the process of oocyte maturation using amphibian (Rana pipiens) fully grown preovulatory ova

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## Abstract The reversibility of cycloheximide inhibition of progesteroneinduced oocyte maturation was investigated. Progesterone treated immature oocytes underwent nuclear (germinal vesicle breakdown) and cytoplasmic maturation unless inhibited by incubation in the continuous presence of cyclohexi