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Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide

✍ Scribed by Shi Yu Yang; Kevin M Sales; Barry J Fuller; Alexander M Seifalian; Marc C Winslet


Book ID
119901981
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
293 KB
Volume
7
Category
Article
ISSN
1476-4598

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## Abstract E‐peptide of the pro‐Insulin‐like growth factor‐I (pro‐IGF‐I) is produced from pre‐pro‐IGF‐I by proteolytic cleavage in the post‐translational processing. Previous in vitro studies conducted in our laboratory showed that Ea4‐peptide of rainbow trout (rt) pro‐IGF‐I or Eb‐peptide of human