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Inducible site-specific recombination in the brain

✍ Scribed by Christoph Kellendonk; François Tronche; Emilio Casanova; Katrin Anlag; Christian Opherk; Günther Schütz


Book ID
115628926
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
361 KB
Volume
285
Category
Article
ISSN
0022-2836

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Inducible site-specific recombination in
✍ Nathalie H. Doerflinger; Wendy B. Macklin; Brian Popko 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 692 KB

## Abstract Summary: To explore the function of genes expressed by myelinating cells we have developed a model system that allows for the inducible ablation of predetermined genes in oligodendrocytes and Schwann cells. The Cre/loxP recombination system provides the opportunity to generate tissue‐sp