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Inducible nitric oxide synthase (iNOS), not neuronal NOS (nNOS) in cardioprotection by fibroblast growth factor-2 (FGF2)

✍ Scribed by Gregory Carpenter; Darius Porter; Siyun Liao; Gilbert Newman; Jo El J. Schultz

Book ID: 116985006
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 51 KB
Volume: 42
Category: Article
ISSN: 0022-2828
DOI: 10.1016/j.yjmcc.2007.03.571

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## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN