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Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

✍ Scribed by Anthony J Kane; Jane E Barker; Geraldine M Mitchell; David R B Theile; Rosalind Romero; Aurora Messina; Milind Wagh; Frankie O G Fraulin; Wayne A Morrison; Alastair G Stewart

Book ID
110005596
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
297 KB
Volume
132
Category
Article
ISSN
0007-1188

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πŸ“œ SIMILAR VOLUMES

Nitric oxide synthase inhibitors improve
Nitric oxide synthase inhibitors improve skin flap survival in the rat
✍ Laura K. Knox; Alastair G. Stewart; Peter G. Hayward; Professor Wayne A. Morriso πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 343 KB

## Abstract The ability of nitric oxide (NO) synthase inhibitors to reduce ischemia‐induced skin flap necrosis was assessed using a modified McFarlane flap in the rat. Flap survival was significantly improved in L‐NIO treated (86 Β± 2%), L‐NAME‐treated (84 Β± 2%), and aminoguanidine‐treated (76 Β± 2%)