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Induces vasodilatation of rat mesenteric arteryin vitromainly by inhibiting receptor-mediated Ca2+-influx and Ca2+-release

โœ Scribed by Yong-Xiao Cao; Jian-Pu Zheng; Jian-Yu He; Jie Li; Cang-Bao Xu; Lars Edvinsson


Publisher
Springer
Year
2005
Tongue
English
Weight
823 KB
Volume
28
Category
Article
ISSN
0253-6269

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## Abstract Galanin activates three receptors, the galanin receptor 1 (GalR1), GalR2, and GalR3. In the gastrointestinal tract, GalR1 mediates the galanin inhibition of cholinergic transmission to the longitudinal muscle and reduction of peristalsis efficiency in the small intestine. Galanin has al