Investigation of the effects of BTS 67 5
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M.J. Cooling; P. Spencer; D. Yates; M.F. Sim; R.B. Jones
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Article
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1999
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John Wiley and Sons
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English
โ 167 KB
BTS 67 582 stimulates insulin release and causes dose-dependent glucose-lowering activity in the conscious beagle dog. Plasma glucose levels were lowered within 1 h and were maximally reduced by 53.2 ยฑ 2.7% 2-3 h after oral dosing with 90 ยตmol/kg BTS 67 582 (equivalent to 22.5 mg/kg as the free base