Studies were made to determine whether freshly isolated monocytes from healthy donors could influence the induction of lymphokine (IL-2)-activated killer (LAK) activity. Highly purified lymphocytes (> 99%) and monocytes (> 90ยฐ/o) were isolated by counter-flow centrifugal elutriation from peripheral
โฆ LIBER โฆ
Indomethacin up-regulates the generation of lymphokine-activated killer-cell activity and antibody-dependent cellular cytotoxicity mediated by interleukin-2
โ Scribed by Avi Eisenthal
- Publisher
- Springer-Verlag
- Year
- 1990
- Tongue
- English
- Weight
- 972 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0340-7004
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We have investigated the effect of pre-treatment with the anti-cancer drugs cisplatin and etoposide on the susceptibility of P815 murine mastocytoma cells to lysis by murine spleen-derived anti-CD3-activated killer-T (AK-T) cells. A 20 hr pre-treatment with cisplatin (0.2-2 microg/ml) or etoposide (