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Indoloditerpenes from an algicolous isolate of Aspergillus oryzae

✍ Scribed by Ming-Feng Qiao; Nai-Yun Ji; Xiang-Hong Liu; Ke Li; Qing-Mei Zhu; Qin-Zhao Xue

Book ID
104004754
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
194 KB
Volume
20
Category
Article
ISSN
0960-894X

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✦ Synopsis

Two new indoloditerpene derivatives asporyzin A (1) and asporyzin B (2), one new indoloditerpene asporyzin C (3), and three known related indoloditerpenes JBIR-03 (4), emindole SB (5), and emeniveol (6) were isolated from an endophytic fungus Aspergillus oryzae, isolated from the marine red alga Heterosiphonia japonica. Their structures were unambiguously established by spectroscopic techniques. In addition, all the isolates were evaluated preliminarily for insecticidal and antimicrobial activities in order to probe into their chemical defensive function. Compound 4 was more active against brine shrimp than the others, and 3 possessed potent activity against Escherichia coli.

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