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Indolmycin Inhibits Prokaryotic Tryptophanyl-tRNA Ligase

✍ Scribed by Rolf G. WERNER; Lance F. THORPE; Wolfgang REUTER; Knud H. NIERHAUS


Book ID
115115556
Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
244 KB
Volume
68
Category
Article
ISSN
1432-1327

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Alterations in the rate of cellular tryptophan metabolism are involved in mediating important biological activities associated with cytokines and growth factors. Indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase are enzymes of tryptophan metabolism whose expression in a variety of c