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Indolizine derivatives with biological activity III: 3-(3-aminopropyl)-2-methylindolizine, 3-(3-aminopropyl)-2-methyl-5,6,7,8-tetrahydroindolizine, and their N-alkyl derivatives

✍ Scribed by Ippolito Antonini; Mario Cardellini; Francesco Claudi; Palmarisa Franchetti; Ugo Gulini; Giuseppe De Caro; Fabrizio Venturi

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 549 KB
Volume: 66
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600661209

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✦ Synopsis

The syntheses and a preliminary pharmacological evaluation of some aminopropylindolizines and aminopropyltetrahydroindolizines are reported. All compounds showed anti-5-hydroxytryptamine, anti-histamine, and antiacetylcholine activities. Some also exhibited weak CNS activity.

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