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Indoleamine 2,3-Dioxygenase is Necessary for Cytolytic Activity of Natural Killer Cells

✍ Scribed by S. Kai; S. Goto; K. Tahara; A. Sasaki; S. Tone; S. Kitano


Book ID
110749516
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
496 KB
Volume
59
Category
Article
ISSN
0300-9475

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## Abstract A dipeptide, L‐glutamyl L‐tryptophan (L‐glu‐L‐trp), was identified in a screen for immunomodulators in the soluble fraction of the thymus. L‐glu‐L‐trp inhibits tumor growth in mice without showing direct cellular toxicity in a variety of human tumor cell lines. L‐glu‐L‐trp antitumor act