Indole alkaloids by a chemoenzymatic approach: two convergent routes for the first enantioselective synthesis of (+)-20R-15,20-dihydrocleavamine

✍ Scribed by Bruno Danieli; Giordano Lesma; Daniele Passarella; Alessandra Silvani

• Book ID: 104210222
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 118 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00404-4

✦ Synopsis

A stereocontrolled total synthesis of the title compound is described, starting from enantiopure intermediates. Two alternative strategies have been developed to ensure the critical formation of the nine-membered ring of 3.