Indole alkaloids. A combined chemical and enzymatic route for eburnane ring construction : Formal synthesis of (−)-Eburnamonine
✍ Scribed by Giovanni Palmisano; Paolo D'Anniballe; Marco Santagostino
- Book ID
- 104203337
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 541 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4020
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A new synthesis of the 2-dimethylamino-4-hydroxy-6-methoxymethyl-3H-imidazo [4', 5' :3,4] pyfido[2,3-b]indole, used as key intermediate in the total synthesis of the alkaloids grossularines -1 and -2. based on the step-wise formation of the pyfidine and imidazole tings, is described.
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