Individualising netilmicin dosing in neonates
โ Scribed by Catherine M. T. Sherwin; Roland S. Broadbent; Natalie J. Medlicott; David M. Reith
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 234 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Multiple regression analyses of data from 33 neonates who received netilmicin therapy showed that concurrent treatment with other drugs (Drg), creatinine clearance (CL,,), gestational age (GA), and an apgar score of less than 6 at 1 min (Agl ') were significant determinants of netilmicin clearance.
The use of bioelectrical impedance (BI) analysis as a non-invasive approach for individualizing gentamicin therapy in newborn infants has been investigated in a two phase study. In Phase I, 1/impedance and length were identified as statistically significant predictors of the distribution volume of g