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Individual telomere length decay in patients with spondyloarthritis

✍ Scribed by Tamayo, María; Pértega, Sonia; Mosquera, Alejandro; Rodríguez, Montserrat; Blanco, Francisco J.; Fernández-Sueiro, José Luis; Gosálvez, Jaime; Fernández, José Luis


Book ID
122158991
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
369 KB
Volume
765
Category
Article
ISSN
0027-5107

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Telomeres play an important role in maintaining chromosomal stability and are often shortened in transformed cells. p53 is the most commonly mutated gene in cancers and its status is thought to reflect the level of genomic stability. We measured telomeric length by Southern blot analysis in cells fr