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Indium(III) Chloride-Catalyzed Propargylation/Amination/Cycloisomerization Tandem Reaction: One-Pot Synthesis of Highly Substituted Pyrroles from Propargylic Alcohols, 1,3-Dicarbonyl Compounds and Primary Amines

✍ Scribed by Xiao-tao Liu; Lei Huang; Fei-jian Zheng; Zhuang-ping Zhan


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
230 KB
Volume
350
Category
Article
ISSN
1615-4150

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✍ Victorio Cadierno; José Gimeno; Noel Nebra 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB

## Abstract A simple and highly efficient method for the preparation of fully substituted pyrroles, from readily accessible secondary propargylic alcohols, 1,3‐dicarbonyl compounds and primary amines, has been developed. The one‐pot multicomponent reaction, which is catalysed by the system [Ru(η^3^