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Indium Trichloride-Mediated Facile Synthesis of 3-(Substituted methylthio)-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole in Water†

✍ Scribed by Song Yang; Bao-An Song; Lin-Hong Jin; De-Yu Hu

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
54 KB
Volume
24
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

An environmentally benign and efficient process for the preparation of 3‐(substituted methylthio)‐4‐phenyl‐5‐ (3,4,5‐trimethoxyphenyl)‐4__H__‐1,2,4‐triazole was achieved by the reaction of 4‐phenyl‐5‐(3,4,5‐trimethoxyphenyl)‐ 4__H__‐1,2,4‐triazole‐3‐thiol with different halides in aqueous media mediated by indium trichloride in high yields.

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