Zirconium-catalyzed Nagata reaction for
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Hongchao Zheng; Dennis G. Hall
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Article
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2010
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Elsevier Science
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French
β 431 KB
An efficient ZrCl 4 catalyzed ortho-hydroxyalkylation of phenols with aldehydes promoted by 3,5-bis (trifluoromethyl)phenyl boronic acid, leading to the formation of 2-aryl-1,3,2-aryldioxaborins was investigated and optimized. The reaction afforded the desired aryldioxaborins in good to excellent yi