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Indispensable role of Bcl2 in the development of the melanocyte stem cell

✍ Scribed by Siu-Shan Mak; Mariko Moriyama; Eri Nishioka; Masatake Osawa; Shin-Ichi Nishikawa


Book ID
116975494
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
758 KB
Volume
291
Category
Article
ISSN
0012-1606

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## Abstract The development of melanocytes from neural crest‐derived precursor cells depends on signaling by the receptor tyrosine kinase KIT and the G protein‐coupled endothelin receptor B (EDNRB) pathways. Loss‐of‐function mutations in either of these two signaling receptor molecules cause a loss