Indications and Results of Liver Transplantation in Patients with Neuroendocrine Tumors
✍ Scribed by Michael Olausson; Styrbjörn Friman; Christian Cahlin; Ola Nilsson; Svante Jansson; Bo Wängberg; Håkan Ahlman
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 154 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0364-2313
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## BACKGROUND. Patients with neuroendocrine gastrointestinal tumors usually present with inoperable metastatic disease and severe hormonal symptoms. Specific chemotherapy, interferon-␣ (IFN), and somatostatin analogs are established therapies for these patients, but all of them eventually fail. Hep
Liver transplantation can be a therapeutic option for individual patients with neuroendocrine tumors metastatic only to the liver. In this consecutive series of 15 patients (5 multivisceral and 10 orthotopic liver transplantations) with well-differentiated carcinoids, or endocrine pancreatic tumors,