Indication and Extent of Surgery in Hereditary Nonpolyposis Colorectal Cancer
β Scribed by Dudukgian, Haig; Cintron, Jose R.
- Book ID
- 122032920
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 170 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1043-1489
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## Abstract Endometrial cancer is the second most common cancer in hereditary nonpolyposis colorectal cancer (HNPCC). It has often been overlooked to explore the possibility of HNPCC in endometrial cancer patients. Our study was to investigate how many HNPCC patients existed among endometrial cance
Segregation analysis of eleven families comprising 2762 individuals indicated compatibility of the data with segregation of a major autosomal dominant gene for hereditary nonpolyposis colorectal cancer. It was estimated that between 71% and 79% of the gene carriers were susceptible and had age of on