Independent synthesis of three types of n-substituted dihydropyrimidines and their reactions with malachite green

✍ Scribed by Choji Kashima; Masao Shimizu; Akira Katoh; Yoshimori Omote

• Book ID: 104216892
• Publisher: Elsevier Science
• Year: 1983
• Tongue: French
• Weight: 204 KB
• Volume: 24
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)81367-2

✦ Synopsis

Pyrimidine-2(1H)-thiones and their corresponding dihydroderivatives were treated with Raney nickel to afford respectively three types of dihydropyrimidine isomers, which reacted with malachite green in similar rate constants to 1-benzyl-1,4-dihydronicotinamide.

The synthesis and reactions of N-substituted 1,4_dihydropyridines and their