## Abstract Cell membranes of Moloney lymphoma cells (YAC, of strain A origin) were solubilized by NP40. The antigenicity of the solubilized protein fraction was assayed by inhibition of the corresponding cytotoxic reaction against YAC target cells. The Moloney leukemia virus (MLV)‐determined cell
Independence of Moloney virus-induced cell-surface antigen and membrane-associated virion antigens in immunoselected lymphoma sublines
✍ Scribed by FENYö, EVA MARIA; KLEIN, GEORGE
- Book ID
- 109698692
- Publisher
- Nature Publishing Group
- Year
- 1976
- Tongue
- English
- Weight
- 343 KB
- Volume
- 260
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/260355a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A membrane antigen from RBL‐5 leukemic cells that was solubilized and partially purified is further characterized in this study. This soluble antigen is capable of immunizing syngeneic hosts to reject neoplastic cells and thus resembles TSTA. It also induces cytotoxic antibody in syngen
## Abstract The internal viral protein, p30^1^, has been identified by cytotoxicity tests using xenogeneic sera, on MuLV‐G‐induced rat lymphoma cells. In this system internal virion antigens, and in particular p30, are cytotoxic target antigens for syngeneic antibody and cell‐mediated cytotoxicity;