Increasing the number of bone marrow suppressor T cells during inhibition of immunogenesis by modifying neurotransmitter activity

The increased expression of receptor act

The increased expression of receptor activator of nuclear-κB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by the bisphosphonate ibandronate

✍ Mireya Fernández; Ana M Pino; Paula Figueroa; Juan P Rodríguez 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 204 KB

## Abstract The receptor activator of nuclear factor‐kappaB ligand (RANKL) and interleukin‐1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma patients. In this work we analyzed RANKL expression in human bone marro