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Increasing the number of 5-HT1A-receptors in cortex and hippocampus does not induce mnemonic deficits in mice

✍ Scribed by Bettina Bert; Jörg-Peter Voigt; Heike Kusserow; Franz Theuring; André Rex; Heidrun Fink


Book ID
113841655
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
389 KB
Volume
92
Category
Article
ISSN
0091-3057

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✍ Christian P. Müller; Heike Thönnessen; Marilia Barros; Carlos Tomaz; Robert J. C 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 758 KB

Cocaine induces an increase in hippocampal and nucleus accumbens (Nac) serotonin (5-HT) concentration parallel to locomotor activation. Both effects can be modulated by systemic 5-HT 1A -receptor agonism/antagonism. Given the contribution of the hippocampus to spontaneous behavioral activity, these