Increasing incidence of both major histological types of esophageal carcinomas among men in Sweden

✍ Scribed by Lars-Erik Hansson; Pär Sparén; Olof Nyrén

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: French
• Weight: 623 KB
• Volume: 54
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910540309

✦ Synopsis

Abstract

Although a rare tumor form, there is evidence that the incidence of esophageal adenocarcinomas is increasing in Western Europe and the US. The aim of this nationwide population‐based study was to describe the secular trends in the incidence rates of adenocarcinoma and squamous‐cell carcinoma of the esophagus over a 28‐year period from I960 to 1987. The Swedish Cancer Registry, complete to more than 95%, was used to identify the cases. The percentage verified by histology rose from 89% to 98%. The age‐standardized incidence rate of adenocarcinoma increased in males from 0.5 per I0^5^ in 1960–63 to 1.1 per 10^5^ in 1984–87, corresponding to an average annual increase of 1.5%. In females the incidence remained stable around 0.2 per I0^5^. The age‐standardized incidence rate of squamous‐cell carcinoma in males increased from 2.9 to 4.0 per 10^5^, corresponding to an average annual increase of 1.0%. In females the rate decreased from 1.4 to 1.2 per I0^5^, corresponding to an annual average decrease of 0.5%. The male/female ratio was 4.6 for adenocarcinoma and 2.7 for squamous‐cell carcinoma of the esophagus. Since the incidence rates of squamous‐cell carcinoma of the esophagus and of adenocarcinoma seem to be rising, there is a great need for well‐planned analytical epidemiological studies of these tumor locations, taking the histological type into consideration.