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Increasing glutathione export by astrocytes: A novel therapeutic principle for the treatment of Alzheimer's disease?

โœ Scribed by Muench, Gerald; Steele, Megan L.


Book ID
122041332
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
40 KB
Volume
6
Category
Article
ISSN
1552-5260

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## Abstract One of the main neuropathological lesions observed in brain autopsy of Alzheimer's disease (AD) patients is the extracellular senile plaques mainly composed of amyloidโ€beta (Aฮฒ) peptide. Recently, treatment strategies have focused on modifying the formation, clearance, and accumulation