Jagged1 (JAG1) mutations in Alagille syn
β
DM Warthen; EC Moore; BM Kamath; JJD Morrissette; P Sanchez; DA Piccoli; ID Kran
π
Article
π
2006
π
John Wiley and Sons
π
English
β 297 KB
π 1 views
Alagille syndrome (AGS) is caused by heterozygous mutations in JAG1, and mutations have been previously reported in about 70% of patients who meet clinical diagnostic criteria. We studied a cohort of 247 clinically well-defined patients, and using an aggressive and sequential screening approach we i