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Increases in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens

✍ Scribed by Louise D. McCullough; John D. Salamone


Book ID
115802766
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
723 KB
Volume
577
Category
Article
ISSN
0006-8993

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Dopamine infused persistently (25 gg/24 h for 13 days) into the nucleus accumbens of rat brain caused phasic increases in spontaneous locomotor activity during the period of infusion. This phasic responding was prevented by lithium administered throughout the infusion period in divided doses (3 x da