Increased upstream methylation has no influence on the overexpression of the parathyroid hormone-related protein gene in squamous cell carcinoma of the lung
β Scribed by R.H Ganderton; R.S.J Briggs
- Book ID
- 117657017
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 498 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0959-8049
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Parathyroid hormoneβrelated protein (PTHrP) is mainly responsible for hypercalcemia in squamous cell carcinomas (SCCs). ## Methods We retrospectively checked the appearance of hypercalcemia among 33 patients who died with head and neck SCC. Serum concentrations of Cβter
Parathyroid hormone-related protein (PTHRP) is expressed in a large number of tumors and is the mediator of parathyroid hormone-like effects seen in humoral hypercalcemia of malignancy. The gene coding for PTHRP has been localised to the short arm of chromosome 12. This is at the same region as the