Fibroblasts cultured from affected skin areas of five patients with cutaneous scleroderma were found to produce increased amounts of collagen when compared with nonaffected control cells. Total RNA was isolated from the cultures and analyzed for its level of proal(1)collagen mRNA by hybridization of
✦ LIBER ✦
Increased type I collagen mRNA levels in cultured scleroderma fibroblasts
✍ Scribed by Veli-Matti Kähäri; Tuula Vuorio; Kirsti Näntö-Salonen; Eero Vuorio
- Book ID
- 119119348
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 485 KB
- Volume
- 781
- Category
- Article
- ISSN
- 0167-4781
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Activation of type I collagen genes in c
✍
Tuula Vuorio; Jyrki K. Mäkelä; Eero Vuorio
📂
Article
📅
1985
🏛
John Wiley and Sons
🌐
English
⚖ 551 KB
Regulation of type I collagen mRNA level
✍
Tilman VOSS; Paul BORNSTEIN
📂
Article
📅
1986
🏛
John Wiley and Sons
🌐
English
⚖ 710 KB
Elevated proα2(I) collagen mRNA levels i
✍
Veli-Matti Kähäri; Petteri Multimäki; Eero Vuorio
📂
Article
📅
1987
🏛
Elsevier Science
🌐
English
⚖ 420 KB
Growth-dependent modulation of type I co
✍
Jyrki K. Mäkelä; Tuula Vuorio; Eero Vuorio
📂
Article
📅
1990
🏛
Elsevier Science
🌐
English
⚖ 541 KB
Interleukin-1 increases collagen product
✍
Veli-Matti Kähäri; Jyrki Heino; Eero Vuorio
📂
Article
📅
1987
🏛
Elsevier Science
🌐
English
⚖ 420 KB
Gallium nitrate increases type I collage
✍
Richard S. Bockman; Peter T. Guidon Jr.; Lydia C. Pan; Roberto Salvatori; Alan K
📂
Article
📅
1993
🏛
John Wiley and Sons
🌐
English
⚖ 838 KB
## Abstract Gallium is a Group IIIa transitional element with therapeutic efficacy in the treatment of metabolic bone disorders. Previously described antiresorptive effects of gallium on osteoclasts are not sufficient to account for the full range of effects of gallium on bone structure and metabol