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Increased susceptibility to urethane-induced lung tumors in mice with decreased expression of connexin43

✍ Scribed by Avanzo, J. L.


Book ID
125422309
Publisher
Oxford University Press
Year
2004
Tongue
English
Weight
966 KB
Volume
25
Category
Article
ISSN
0143-3334

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## Abstract Acute apoptotic response to genotoxic carcinogens (AARGC) might be important for controlling the consequences of mutational load in the colon. It has been shown to occur in parallel with activation of DNA repair mechanisms. Inadequate AARGC might allow development of mutated clones with