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Increased susceptibility to degradation by trypsin and subtilisin of in vitro peroxidized myelin proteins

โœ Scribed by E. R. Bongarzone; E. F. Soto; J. M. Pasquini


Publisher
Springer
Year
1995
Tongue
English
Weight
812 KB
Volume
20
Category
Article
ISSN
0364-3190

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Oxidative damage to proteins and lipids
โœ E. R. Bongarzone; J. M. Pasquini; E. F. Soto ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 857 KB

## Abstract Purified myelin isolated from 70โ€dayโ€old rats was submitted to nonenzymatic peroxidative systems containing 100 ฮผM FeC1~3~.6H~2~O,100 ฮผM ascorbic acid, and 100 ฮผM CuSO~4~.6H~2~O 10 mM H~2~O~2~ in order to investigate the extent of damage produced by reactive oxygen species (ROS). Iron a