Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
✍ Scribed by Cabot, Richard C.; Harris, Nancy Lee; Rosenberg, Eric S.; Shepard, Jo-Anne O.; Cort, Alice M.; Ebeling, Sally H.; McDonald, Emily K.; Scher, Howard I.; Fizazi, Karim; Saad, Fred; Taplin, Mary-Ellen; Sternberg, Cora N.; Miller, Kurt; de Wit, Ronald; Mulders, Peter; Chi, Kim N.; Shore, Neal D.; Armstrong, Andrew J.; Flaig, Thomas W.; Fléchon, Aude; Mainwaring, Paul; Fleming, Mark; Hainsworth, John D.; Hirmand, Mohammad; Selby, Bryan; Seely, Lynn; de Bono, Johann S.
- Book ID
- 118044559
- Publisher
- Massachusetts Medical Society
- Year
- 2012
- Tongue
- English
- Weight
- 627 KB
- Volume
- 367
- Category
- Article
- ISSN
- 0096-6762
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Twenty-eight patients with lung cancer, 26 with extensive disease, were treated with the drugs Cytoxan (Cyt) and methotrexate (MTX). The schedule was based on cellular kinetics concepts. Initial therapy was with Cyt 1.1 g/m2 (intravenously) followed by MTX 20 mg/m2 orally, twice weekly, started 9 da