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Increased Survival in Mice Inoculated with Tumor Cells and Treated with Interferon Preparations

✍ Scribed by I. Gresser, C. Bourali, J. P. Lévy, D. Fontaine-Brouty-Boyé and M. T. Thomas


Book ID
123648905
Publisher
National Academy of Sciences
Year
1969
Tongue
English
Weight
892 KB
Volume
63
Category
Article
ISSN
0027-8424

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Nude mice were inoculated with CHOIIFN-y cells, a line of Chinese hamster ovary tumor cells, that had been genetically engineered to produce murine IFN-y. Severe cachexia, as evident from body weight loss and reduced food intake, occurred in these mice, but not in those injected with CHOI control ce