Severe cachexia in mice inoculated with
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Patrick Matthys; Roger Dukmans; Paul Proost; Jo Van Damme; Hubertine Heremans; H
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Article
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1991
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John Wiley and Sons
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French
⚖ 725 KB
Nude mice were inoculated with CHOIIFN-y cells, a line of Chinese hamster ovary tumor cells, that had been genetically engineered to produce murine IFN-y. Severe cachexia, as evident from body weight loss and reduced food intake, occurred in these mice, but not in those injected with CHOI control ce