Increased survival in dogs with malignant mammary tumours overexpressing HER-2 protein and detection of a silent single nucleotide polymorphism in the canine HER-2 gene

A single nucleotide polymorphism in the

A single nucleotide polymorphism in the transmembrane domain coding region of HER-2 is associated with development and malignant phenotype of gastric cancer

✍ Kazuya Kuraoka; Shunji Matsumura; Yoichi Hamai; Kei Nakachi; Kazue Imai; Keisuke 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 113 KB 👁 1 views

Alterations of the HER-2 (erbB-2/neu) proto-oncogene have been associated with carcinogenesis and poor prognosis of certain cancers. A single nucleotide polymorphism (Ile/Val, A/G) in the transmembrane domain was reported to be associated with a risk of breast cancer. In our study, we examined the a