Increased skeletal muscle acetylcholinesterase activity in porcine malignant hyperthermia
β Scribed by Dr. James R. Mickelson; Hemant S. Thatte; Terrrence M. Beaudry; Esther M. Gallant; Charles F. Louis
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 416 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0148-639X
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Electromechanical properties of skeletal muscle were compared between malignant hyperthermia (MH)-susceptible and control pigs. These muscle properties were studied both in vivo and in vitro. The in vivo time interval from nerve stimulation to onset of mechanical tension was longer in muscle of pigs
In rats, acetylcholinesterase (AChE) activity in the fast muscles is several times higher than in the slow soleus muscle. The hypothesis that specific neural impulse patterns in fast or slow muscles are responsible for different AChE activities was tested by altering the neural activation pattern in