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Increased sensitivity of the hippocampus in ethanol-dependent rats to toxic effect ofN-methyl-D-aspartic acid in vivo

โœ Scribed by Mark D. Davidson; Peter Wilce; Brian C. Shanley


Book ID
115804471
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
478 KB
Volume
606
Category
Article
ISSN
0006-8993

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This study investigated the modulatory actions of adenosine and โฅ-aminobutyric acid (GABA) on several aspects of N-methyl-Daspartate (NMDA)-induced neurotoxicity, including neuronal loss, atrophy, necrosis, and calcium accumulation in the hippocampus. For this purpose, we combined unilateral intrahi