Pretreatment with mixed-function oxidase
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J. G. Shaddock; R. H. Heflich; D. C. McMillan; J. A. Hinson; D. A. Casciano
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Article
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1989
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John Wiley and Sons
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English
โ 752 KB
A recent National Toxicology Program evaluation indicates that the rat hepatocyte/DNA repair assay has a high false-negative rate and that it is insensitive to some genotoxic hepatocarcinogens as well as other species and organ-specific carcinogens. In this study, we examined whether the sensitivity