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Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters

✍ Scribed by Tomohiro Sawa; Mounia Mounawar; Masayuki Tatemichi; Isabelle Gilibert; Takahiko Katoh; Hiroshi Ohshima


Book ID
116334803
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
217 KB
Volume
269
Category
Article
ISSN
0304-3835

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## Abstract __Heme oxygenase‐1__ (__HO‐1__) has been demonstrated to play an important role in the regulation of signaling systems, which are involved in the control of cell cycle progression and apoptosis. Recently, a (GT)n dinucleotide repeat polymorphism in the __HO‐1__ promoter was shown to mod