## Abstract ## BACKGROUND Brain metastases (BM) are the most common intracranial tumors in adults. To the authors' knowledge, established prognostic factors for survival after the diagnosis of BM in breast cancer patients do not take into account HERβ2 status, which may have increasing relevance i
β¦ LIBER β¦
Increased risk of brain metastases in patients with HER-2/neu-positive breast carcinoma
β Scribed by Ramin Altaha; Edward Crowell; Gerry Hobbs; Gerry Higa; Jame Abraham
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 40 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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## Abstract ## BACKGROUND Trastuzumab, which is a large monoclonal antibody that is efficacious in the treatment of patients with HERβ2/__neu__βoverexpressing, metastatic breast carcinoma, does not penetrate the bloodβbrain barrier and, thus, may allow the brain to become a sanctuary site for micr