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Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus

✍ Scribed by Rachel Miller-Lotan; Yehuda Herskowitz; Shiri Kalet-Litman; Farid Nakhoul; Doron Aronson; Roaa Zoabi; Roy Asaf; Ofer Ben-Izhak; Edmond Sabo; Sai-Kiang Lim; Heinz Baumann; Franklin G. Berger; Andrew P. Levy


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
99 KB
Volume
21
Category
Article
ISSN
1520-7552

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## Abstract ## Background Individuals with diabetes mellitus (DM) homozygous for the haptoglobin (Hp) 1 allele are at decreased risk of retinopathy as compared to DM individuals with the Hp 2 allele. We sought to recapitulate these findings in DM mice genetically modified at the Hp locus. ## Meth