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Increased Radiosensitivity by a Combination of 9-cis-Retinoic Acid and Interferon-γ in Breast Cancer Cells

✍ Scribed by Gudrun H. Windbichler; Emil Hensler; Martin Widschwendter; Andrea Posch; Günter Daxenbichler; Esther Fritsch; Christian Marth


Book ID
115616867
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
147 KB
Volume
61
Category
Article
ISSN
0090-8258

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Retinoids modulate several cell functions and especially inhibit the growth of a wide variety of cells including breast cancer. Retinoic acid receptor-gamma (RAR-gamma) has been shown to mediate the antiproliferative activity of retinoids. To further test this hypothesis we examined the effects of d