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Increased proto-oncogene expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases

✍ Scribed by D. T. Boumpas; Dr. G. C. Tsokos; D. L. Mann; E. G. Eleftheriades; C. C. Harris; G. E. Mark


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
602 KB
Volume
29
Category
Article
ISSN
0004-3591

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The expression of c-myc, c-myb, and eras protooncogenes, determined using RNA hybridization techniques (slot-blot), was significantly increased in peripheral blood T lymphocytes, but not in B cells, from 17 patients with systemic sclerosis with diffuse scleroderma, compared with the expression in no